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Opioid Equianalgesic Conversion Calculator

Calculates the Equivalent Opioid Dose (OME) and converts between common opioids (Morphine, Oxycodone, Hydromorphone, Methadone, Tramadol, Codeine), considering dose-dependent ratios and route. Always verify results clinically.

FOR PROFESSIONAL USE ONLY

This calculator is a support tool intended exclusively for health professionals. It does not replace clinical judgment. The final decision regarding diagnosis and treatment is the sole responsibility of the professional.

pharmacology

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About this Calculator 💡

An equianalgesic opioid converter is a foundational tool in pain management, used by healthcare professionals to calculate the equianalgesic dose when switching a patient from one opioid to another (opioid rotation) or when changing the route of administration (e.g., from oral to intravenous). This tool is essential because different opioids (such as morphine, oxycodone, hydromorphone, and methadone) possess vastly different analgesic potencies. The converter uses established conversion factors, which represent the dose ratio required to achieve the same level of pain relief between the drugs. It's crucial to note that conversion to certain opioids, especially Methadone, is often dose-dependent, requiring more conservative (higher) conversion factors for higher doses of the source opioid. Correct use of this converter is vital for preventing underdosing (which results in uncontrolled pain) and overdosing (which increases the risk of potentially fatal respiratory depression and other adverse effects), ensuring a safe and effective therapeutic transition.

Reference Values

  • • Equivalent daily dose of the converted opioid

Formula

Calculated by converting the source dose to Oral Morphine Equivalent (OME) and then converting OME to the target opioid dose, using standard MED multipliers.

Reference

  • •ASPM Pain Management Guidelines (American Society for Pain Management Nursing) - Equianalgesic Tables.
  • •WHO Guidelines on the management of chronic pain in children (World Health Organization).
  • •MSD Manuals Professional Version - Opioid Analgesic Equianalgesic Dosing Table.
  • •NCCN Clinical Practice Guidelines in Oncology (National Comprehensive Cancer Network) - Pain Management (for dose-dependent Methadone factors).
  • •Brazilian or European Palliative Care and Pain Guidelines and Consensus (e.g., ANCP, EAPC) - Opioid Conversion Factors.