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GRACE Risk Score for ACS

Estimates in-hospital and 6-month mortality risk for patients with Acute Coronary Syndrome (ACS).

FOR PROFESSIONAL USE ONLY

This calculator is a support tool intended exclusively for health professionals. It does not replace clinical judgment. The final decision regarding diagnosis and treatment is the sole responsibility of the professional.

cardiology

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About this Calculator 💡

The GRACE Score (Global Registry of Acute Coronary Events) is a widely used risk stratification tool in cardiology for patients presenting with an acute coronary syndrome (ACS), such as myocardial infarction or unstable angina. This score calculates the risk of in-hospital mortality and also long-term mortality (usually at 6 months) after the acute event. To do this, it combines several clinical and presentation factors, including age, heart rate, systolic blood pressure, serum creatinine level, Killip class (which assesses signs of heart failure), occurrence of cardiac arrest on admission, ST-segment deviation on the electrocardiogram, and elevated cardiac biomarkers (such as troponin).

Reference Values

  • • In-hospital Mortality: Low Risk (<1%)
  • • In-hospital Mortality: Intermediate Risk (1-3%)
  • • In-hospital Mortality: High Risk (>3%)
  • • 6-month Mortality: Low Risk (<3%)
  • • 6-month Mortality: Intermediate Risk (3-8%)
  • • 6-month Mortality: High Risk (>8%)

Formula

The score is calculated by summing points assigned to 8 clinical variables with specific weights: Age (0-100 pts), Heart Rate (0-46 pts), Systolic BP (0-58 pts), Creatinine (1-28 pts), Killip Class (0-59 pts), Cardiac Arrest at admission (39 pts), ST-segment deviation (28 pts), and elevated cardiac markers (14 pts). The total score ranges from 0 to 372.

Reference

Granger CB, Goldberg RJ, Dabbous O, et al. Predictors of hospital mortality in the global registry of acute coronary events. Arch Intern Med. 2003;163(19):2345-53.